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cholesterol-lowering medications such as cholestyramine (Prevalite, Questran) or colestipol (Colestid); isotretinoin (Accutane); tretinoin (Renova, Retin-A, Vesanoid); an antacid such as Tums, Rolaids, Milk of Magnesia, Maalox, and others; a product that contains bismuth subsalicylate such as Pepto-Bismol; minerals such as iron, zinc, calcium, magnesium, and over-the-counter vitamin and mineral supplements; a blood thinner such as warfarin (Coumadin, Jantoven); or a penicillin antibiotic such as amoxicillin (Amoxil, Augmentin, Dispermox, Moxatag), ampicillin (Principen, Unasyn), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), or penicillin (Bicillin L-A, PC Pen VK, Pfizerpen). If you have diabetes, doxycycline can cause false results in some tests for sugar in the urine. Check with your doctor before changing your diet or the dosage of your diabetes medicine. Keep all appointments with your doctor and laboratory. Your doctor will want to check your response to doxycycline. Previously, doxycycline was believed to impair the effectiveness of many types of hormonal contraception due to CYP450 induction. Recent research has shown no significant loss of effectiveness in oral contraceptives while using most tetracycline antibiotics (including doxycycline), although many physicians still recommend the use of barrier contraception for people taking the drug to prevent unwanted pregnancy.
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