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CLS 308 - Hepatitis
Question | Answer |
---|---|
List the types of Hepatitis | A - Infectious B, D - Serum C - Parenterally transmitted E - Enterically transmitted G - Others |
What are the causes of viral hepatitis? | Hep A, B, C, D, E, and G Cytomegalovirus Epstein-Barr Herpes Simplex |
Clinical manifestations of Hepatitis | Flu-like symptoms, Fatigue, Fever, Myalgia, Loss of appetite, Nausea, Vomiting, Diarrhea, Hepatomegaly |
Lab findings of Hepatitis | Dark urine, light feces, Increased bilirubin, Liver enzymes increased |
How is Hepatitis A transmitted? | Fecal-Oral route |
What is the time frame of a Hepatitis A infection? | Incubation period of 28 days. Abrupt onset. 1-8 weeks. Resolves itself. No chronic state |
What is the treatment of Hep. A? | Gamma Globulins given to immuno compromised patients exposed to Hep. A. |
What are the preventions of Hep. A? | Proper personal hygiene, Proper sanitation, and Vaccination. |
How is Hep. E transmitted? | Fecal-oral route. RNA virus. |
List the tests used to diagnose Hep. E. | Anti-HEV IgM Anti-HEV IgG HEV RNA ELISA Western Blot Fluorescent antibody blocking assay HEV RNA - PCR |
How is Hepatitis B transmitted? | Parenteral Route |
What are the clinical manifestations of Hep. B? | Chronic HBV, Cirrhosis, Hepatocellular carcinoma. May be asymptomatic. |
What are the markers used in Hep. B? | HBsAG - Hep B Surface Ag (1st active) HBeAG - Hep B Envelope Ag (2nd) IgM anti-HBc - Hep B core Anti-HBe Anti-HBs |
How can Hepatitis B be prevented? | Prevent transmission Vaccinations |
What is the occurrence of infection of Hepatitis D? | Hep D is parenterally transmitted with the presence of Hep B. |
How is Hep C transmitted? | Unprotected sex, Blood/body fluid exposure, IV drug use. |
What are the clinical manifestations of Hep C? | Hepatocellular carcinoma chronic infection with cirrhosis immune complexes. |
What are the outcomes of Hepatitis C? | Most continue the infection, becoming chronically ill or a carrier. |
What are the lab findings of Hep C? | Anti-HCV |
How is Hepatitis G transmitted? | Blood borne |
What tests are used in determining Hep G? | ELISA, HGV RNA, and Western blot |