{{ isErrorSetToBasket === false ? 'Товар добавлен вкорзину' : 'Не удалось добавить товар в корзину'}}
Перейти в корзину
{{Object.keys(error)[0]}}:
{{Object.values(error)[0]}}
Цена По запросу
Количество
Вы уже добавили максимально доступное на складе кол-во товара
Достигнуто максимально доступное кол-во
Под заказ
{{!!storageProduct ? 'На складе' : 'Под заказ'}}
Ожидается поставка
Description_x000D_
General description_x000D_
TDP-43 (TAR DNA binding protein) belongs to the family of heterogeneous nuclear ribonucleoproteins (hnRNPs), that binds single stranded RNA. TDP-43 has been implicated in the transcription regulation of HIV. TDP-43 is the major ubiquinated component of cytoplasmic inclusions in frontotemporal lobe degeneration subtype FTLD-U and amyotrophic lateral sclerosis (ALS). TDP-43 is predominantly localized to the nucleus._x000D_
Immunogen_x000D_
synthetic peptide containing phosphorylated Ser410 of human TDP-43, conjugated to KLH. The corresponding sequence is identical in mouse TDP-43._x000D_
Application_x000D_
Anti-phospho-TDP-43 (pSer410) antibody produced in rabbit has been used in immunoblotting._x000D_
Physical form_x000D_
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide._x000D_
Disclaimer_x000D_
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_
Biochem/physiol Actions_x000D_
Pathological TDP-43 forms abnormal inclusions in neuronal perikarya and neurites. Several pathogenic TDP-43 mutations have been identified in familial amyotrophic lateral sclerosis (ALS).
- Related Categories ALS, Prion Disease, and Others, ALS, Prion Disease, and others, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Antibodies for Neurobiology, Antibodies for Neurodegenerative Diseases Research, Antibodies to Phosphoproteins at Phosphoserine (pSer), Neuroscience, PH-PI, Phosphoserine, Phosphothreonine, and Phosphotyrosine Antibodies, Primary AntibodiesMore... conjugate